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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2C
All Species:
15.45
Human Site:
S600
Identified Species:
42.5
UniProt:
Q8IUH8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUH8
NP_787078.1
684
74503
S600
N
P
E
D
R
S
D
S
S
E
G
W
S
D
A
Chimpanzee
Pan troglodytes
XP_523673
684
74537
S600
N
P
E
D
R
S
D
S
C
E
G
W
S
D
A
Rhesus Macaque
Macaca mulatta
XP_001115879
684
74573
S600
N
P
E
D
R
S
D
S
S
E
G
W
S
D
A
Dog
Lupus familis
XP_548046
660
70155
S586
G
L
D
V
H
S
D
S
S
E
G
W
R
D
A
Cat
Felis silvestris
Mouse
Mus musculus
A2A6C4
690
76248
S614
S
P
E
G
H
S
E
S
S
E
G
W
S
D
T
Rat
Rattus norvegicus
Q5PQL3
577
63718
A507
A
P
Q
T
P
W
A
A
P
Q
G
P
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
L574
E
G
Q
T
L
S
A
L
G
Q
P
E
R
P
A
Chicken
Gallus gallus
Q5F383
596
66378
P526
L
P
K
D
S
N
V
P
A
S
Q
Q
E
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
K442
H
T
F
D
L
K
V
K
S
P
R
I
Y
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.4
70.4
N.A.
69.1
41.5
N.A.
33
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
99.1
96.1
78.3
N.A.
80.2
57.5
N.A.
51
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
47.5
P-Site Identity:
100
93.3
100
60
N.A.
66.6
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
100
66.6
N.A.
80
33.3
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
23
12
12
0
0
0
0
0
56
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
12
56
0
0
45
0
0
0
0
0
0
56
0
% D
% Glu:
12
0
45
0
0
0
12
0
0
56
0
12
12
0
12
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
12
0
0
0
0
12
0
67
0
0
0
0
% G
% His:
12
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% I
% Lys:
0
0
12
0
0
12
0
12
0
0
0
0
0
0
0
% K
% Leu:
12
12
0
0
23
0
0
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
67
0
0
12
0
0
12
12
12
12
12
0
23
12
% P
% Gln:
0
0
23
0
0
0
0
0
0
23
12
12
0
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
0
0
12
0
23
0
0
% R
% Ser:
12
0
0
0
12
67
0
56
56
12
0
0
45
0
0
% S
% Thr:
0
12
0
23
0
0
0
0
0
0
0
0
0
12
12
% T
% Val:
0
0
0
12
0
0
23
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
56
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _